منابع مشابه
Interaction and transport of thiazide diuretics, loop diuretics, and acetazolamide via rat renal organic anion transporter rOAT1.
The renal tubular secretion of thiazides and loop diuretics via the organic anion transport system in renal tubules is required for them to reach their principal sites of action. Similarly, acetazolamide, a diuretic clinically administered for glaucoma, is excreted from the kidney by glomerular filtration and tubular secretion. In this study, we investigated the interaction and transport of the...
متن کاملDiuretics and mortality in acute renal failure.
OBJECTIVE According to recent research, diuretics may increase mortality in acute renal failure patients. The administration of diuretics in such patients has been discouraged. Our objective was to determine the impact of diuretics on the mortality rate of critically ill patients with acute renal failure. DESIGN Prospective, multiple-center, multinational epidemiologic study. SETTING Intens...
متن کاملSodium Chloride Transport by Rabbit
The results of the present study indicate that NaC1 transport by in vitro rabbit gallbladder must be a consequence of a neutral coupled carriermediated mechanism that ultimately results in the active absorption of both ions; pure electrical coupling between the movements of Na and C1 can be excluded on the grounds of electrophysiologic considerations. Studies on the unidirectional influxes of N...
متن کاملElectromotive Chloride Transport and Gastric Acid Secretion
The total active transport of chloride ions across the gastric mucosa can be considered as the sum of two fractions; an acidic one which is equivalent to the acid secreted, and an electromotive one which accounts for the electric energy generated by the gastric mucosa. In the present studies, the relationship between this electromotive chloride transport and acid secretion has been investigated...
متن کاملORIGINAL CONTRIBUTION Diuretics, Mortality, and Nonrecovery of Renal Function in Acute Renal Failure
ACUTE RENAL FAILURE (ARF) IN hospitalized patients may be associated with low, normal, or excess extracellular volume, depending on the cause of the ARF, accompanying conditions (eg, heart failure, liver disease), and patterns of administration of crystalloids and colloids. Diuretic agents are frequently given to augment renal salt and water excretion in the setting of extracellular volume over...
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ژورنال
عنوان ژورنال: Circulation
سال: 1976
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.53.4.587